Shengping Hou Selected Research

Uveitis

3/2024	YY1 Lactylation Aggravates Autoimmune Uveitis by Enhancing Microglial Functions via Inflammatory Genes.
11/2023	A de novo missense mutation in MPP2 confers an increased risk of Vogt-Koyanagi-Harada disease as shown by trio-based whole-exome sequencing.
9/2023	FTO-mediated m6A modification alleviates autoimmune uveitis by regulating microglia phenotypes via the GPC4/TLR4/NF-κB signaling axis.
1/2023	Apigenin Alleviates Autoimmune Uveitis by Inhibiting Microglia M1 Pro-Inflammatory Polarization.
1/2023	NLRP3 Attenuates Intraocular Inflammation by Inhibiting AIM2-Mediated Pyroptosis Through the Phosphorylated Salt-Inducible Kinase 1/Sterol Regulatory Element Binding Transcription Factor 1 Pathway.
1/2023	Integrative Single-Cell Transcriptomics and Epigenomics Mapping of the Fetal Retina Developmental Dynamics.
1/2022	N6-methyladenosine demethylase FTO regulates inflammatory cytokine secretion and tight junctions in retinal pigment epithelium cells.
1/2022	Galectin-3 regulates microglial activation and promotes inflammation through TLR4/MyD88/NF-kB in experimental autoimmune uveitis.
1/2022	Icariin alleviates uveitis by targeting peroxiredoxin 3 to modulate retinal microglia M1/M2 phenotypic polarization.
1/2021	Low Expression of YTH Domain-Containing 1 Promotes Microglial M1 Polarization by Reducing the Stability of Sirtuin 1 mRNA.

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Shengping Hou Research Topics

Disease

26	Uveitis 03/2024 - 01/2010
26	Uveomeningoencephalitic Syndrome (Vogt Koyanagi Harada Syndrome) 11/2019 - 01/2008
16	Behcet Syndrome (Behcet's Syndrome) 02/2023 - 07/2010
15	Autoimmune Diseases (Autoimmune Disease) 10/2023 - 01/2008
9	Inflammation (Inflammations) 09/2023 - 01/2013
8	Anterior Uveitis 01/2017 - 01/2013
7	Ankylosing Spondylitis 01/2017 - 01/2013
3	Genetic Predisposition to Disease (Genetic Predisposition) 01/2020 - 01/2013
2	AIDS-Related Complex (ARC) 12/2023 - 01/2011
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 02/2023 - 01/2022
2	Vision Disorders (Hemeralopia) 02/2023 - 01/2022
2	Hypoxia (Hypoxemia) 01/2023 - 01/2022
2	Neoplasms (Cancer) 01/2022 - 01/2020
2	Cataract (Cataracts) 01/2019 - 01/2011
2	Necrosis 01/2018 - 01/2014
2	Retinal Vasculitis 01/2013 - 01/2013
1	Diabetic Retinopathy (Retinopathy, Diabetic) 02/2024
1	Rheumatoid Arthritis 02/2023
1	Retinal Degeneration 02/2023
1	Ganglion Cysts (Ganglion) 02/2023
1	Macular Degeneration (Age-Related Maculopathy) 01/2023
1	Retinal Neovascularization 01/2023
1	Neuroinflammatory Diseases 01/2022
1	Blindness (Hysterical Blindness) 01/2022
1	Colitis 01/2022
1	Retinal Diseases 01/2022
1	Immune System Diseases (Immune Disorders) 01/2021
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2020
1	Neoplasm Metastasis (Metastasis) 01/2020
1	Virus Diseases (Viral Diseases) 01/2020
1	Fibrosis (Cirrhosis) 01/2020
1	Autosomal Dominant Cataract 01/2019
1	Tinnitus 01/2019
1	Headache (Headaches) 01/2019
1	Alopecia (Baldness) 01/2019

Drug/Important Bio-Agent (IBA)

11	Retinaldehyde (Retinal)IBA 03/2024 - 01/2021
7	Proteins (Proteins, Gene)FDA Link 10/2023 - 11/2013
4	Interleukin-17 (Interleukin 17)IBA 01/2018 - 07/2010
4	InterleukinsIBA 01/2015 - 10/2010
3	CytokinesIBA 03/2024 - 01/2016
3	RNA (Ribonucleic Acid)IBA 02/2024 - 01/2021
3	6-methyladenineIBA 09/2023 - 01/2020
3	Transcription Factors (Transcription Factor)IBA 01/2023 - 04/2016
3	InflammasomesIBA 01/2023 - 01/2021
3	Messenger RNA (mRNA)IBA 01/2019 - 01/2013
3	P-2 (P 2)IBA 01/2019 - 02/2014
3	MicroRNAs (MicroRNA)IBA 01/2017 - 12/2013
3	HLA Antigens (Human Leukocyte Antigens)IBA 03/2016 - 01/2008
3	Interleukin-10 (Interleukin 10)IBA 01/2015 - 01/2014
2	Small Cytoplasmic RNAIBA 02/2024 - 09/2023
2	Long Noncoding RNAIBA 02/2023 - 11/2019
2	Carrier Proteins (Binding Protein)IBA 01/2022 - 04/2016
2	beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA 01/2020 - 09/2014
2	Protein Kinase C-thetaIBA 01/2019 - 01/2016
2	LigandsIBA 01/2018 - 01/2011
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2016 - 06/2014
2	Complement System Proteins (Complement)IBA 08/2015 - 01/2015
2	Complement C4 (Complement Component 4)IBA 01/2015 - 11/2013
2	TNF Receptor-Associated Factor 5IBA 01/2014 - 01/2013
2	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 05/2013 - 01/2012
2	Monocyte Chemoattractant ProteinsIBA 01/2010 - 08/2009
2	HLA-DR53IBA 05/2009 - 01/2008
2	HLA-DR4 Antigen (HLA DR4 Antigen)IBA 05/2009 - 01/2008
2	Fc Receptors (Fc Receptor)IBA 05/2009 - 01/2008
1	CarbonIBA 12/2023
1	AcidsIBA 12/2023
1	GasesIBA 12/2023
1	GraphiteIBA 12/2023
1	SootIBA 12/2023
1	BuffersIBA 12/2023
1	ethyl 6- (N- (2- chloro- 4- fluorophenyl)sulfamoyl)cyclohex- 1- ene- 1- carboxylateIBA 09/2023
1	Alpha-Ketoglutarate-Dependent Dioxygenase FTOIBA 09/2023
1	GlypicansIBA 09/2023
1	6-pyruvoyltetrahydropterin synthase (PTPS)IBA 02/2023
1	Protein Tyrosine PhosphatasesIBA 02/2023
1	pexidartinibIBA 01/2023
1	ElementsIBA 01/2023
1	Oxygen (Dioxygen)IBA 01/2023
1	Phosphotransferases (Kinase)IBA 01/2023
1	SaltsIBA 01/2023
1	SterolsIBA 01/2023
1	Macrophage Colony-Stimulating FactorIBA 01/2023
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2023
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2023
1	Therapeutic UsesIBA 01/2023
1	ApigeninIBA 01/2023
1	LipopolysaccharidesIBA 01/2022
1	N-methyladenosineIBA 01/2022
1	Galectin 3 (LGALS3)IBA 01/2022
1	Cysteine (L-Cysteine)FDA Link 01/2022
1	LectinsIBA 01/2022
1	Peroxiredoxin IIIIBA 01/2022
1	NF-kappa B (NF-kB)IBA 01/2022
1	Scavenger Receptors (Scavenger Receptor)IBA 01/2022
1	icariinIBA 01/2022
1	Retinoic Acid Receptors (Retinoic Acid Receptor)IBA 01/2020
1	Acetic Acid (Vinegar)FDA LinkGeneric 01/2020
1	Crystallins (Crystallin)IBA 01/2019

Therapy/Procedure

4	Therapeutics 02/2023 - 01/2020
1	Traditional Medicine (Folk Remedies) 01/2022